最新国产福利在线观看精品_99视频只有精品_日韩亚洲亚洲综合_免费黄色一级毛片_美女黄裸身无遮挡免费观看的网站_国产精品久久孕妇大杂乱_91看片淫黃大片_欧美一区4卡黑人_欧美成人国产高清视频_三级在线的特黄视频网站

收縮
PRODUCTS
PRODUCTS
Your current location:Home > Our Products >> Animal Models
BREAST CANCER
 

Orthotopic breast cancer models are suitable for testing the efficacy of drug compounds against primary tumor growth in the proper tissue microenvironment. They involve inoculation of breast cancer cells into the mammary fat pad, leading to development of a primary mammary tumor to the site of inoculation. Pharmatest offers orthotopic breast cancer models with either human estrogen receptor positive MCF-7 cell line or triple negative human MDA-MB-231(SA) or mouse 4T1 cell lines. Tumor growth is monitored by measuring the dimensions of the tumor at desired intervals during the experiment. At the end of the experiment, the primary tumor and selected organs are collected for further analysis. In the case of the triple negative cell lines, metastasis to various distant sites, such as lungs can also be rapidly determined by ex vivo fluorescence imaging. Several additional parameters can be studied by immunohistochemistry, including angiogenesis, hypoxia, proliferation rate and apoptosis.

Breast cancer metastasis models are suitable for testing the efficacy of drug compounds against several dissemination processes and growth in specific microenvironments. The metastasis models are demanding for the drug candidate, but they have an excellent clinical predictivity. Our intracardiac breast cancer bone metastasis models are clinically predictive models of cancer-induced bone disease. Radiography and dynamic fluorescence imaging reveal the progression of the disease. The data is analyzed for tumor burden, and in bone metastasis studies also bone lesion number and area. Histological bone samples can be analyzed for tumor area, trabecular bone area and osteoclast number to reveal detailed information about the test compound's effects on bone metastases.

HomeAbout usNews CentreProducts CentreRecruitmentContact us
© Copyright Beijing Rongzhi Haida Biotech Co., Ltd.
Beijing headquarters Tel:+86.10.5889.5809 +86.10.5889.5646 Fax: +86.10.5889.5611 E-mail:market@rz-biotech.com
(BJ)ICP12047214 Technical support:wanmeiweb.com